HGH (Human Growth Hormone) [Somatropin] [Kigtropin]

Company: Kigtropin (China)

Usage: injectable

Description Kigtropin (Human Growth Hormone)

Today pharmaceutical companies produce Human Growth Hormone (HGH) by recombinant technology (rhGH). It is an injectable substance which looks like white powder. rhGH is an absolute copy of natural growth hormone, which consists of 191 amino acids, has molecular formula C990H1528N262O300S7 and molecular weight – 22,125 Daltons.

There are different opinions about Kigtropin. Some athletes consider it a wonder drug, which provides enormous strength and muscle gain in a short period of time. Others think that it is useless for athletic purposes and can be helpful only for children suffering from stunting.

There is also an opinion that it can cause overgrowth of bones in adults (jaw and limbs). Besides, there is misunderstanding about the dosages and which version of HGH is better – natural, synthetic or recombined.

In order to solve this controversy we have to closely examine the growth hormone. It is a polypeptide hormone which consists of 191 amino acids. HGH is released from hypophysis during training, sleep, stress or low blood sugar.

However it doesn’t affect directly, but stimulates production of insulin-like growth factors (IGF) and somatomedins in the liver. Thus, Kigtropin causes different effects in the body. As liver can produce only definite amount of IGF and somatomedins, the effect of HGH has limitation.

Somatotropic Hormones

The use of these somatotropic hormones (STH) produces three effects:

• Anabolic effect occurs due to increase of protein synthesis which leads to hypertrophy of muscle cells. Besides, they also cause muscular hyperplasia which you cannot get with steroids. This is why STH has reputation of the strongest anabolic hormone.
• Fat burning effect converts body fat into energy and allows you to increase intake of calories.
• Strengthening of connective tissues, tendons and cartilages. Probably this is one of the main reasons of strength increase in athletes. So, if you take STH along with steroids it can protect you from injuries and increase your strength at the same time.

The reasons of ineffectiveness

Nevertheless some athletes were disappointed in HGH results. This can happen due to several reasons:

1. HGH is rather expensive substance and not everyone can afford it. So, if you take insufficient dose, or take it irregularly or not for necessary period of time it can lead to worsening of results.
2. When you use HGH your body also requires more other hormones (thyroid hormone, insulin, corticosteroids, gonadotropins, estrogens, androgens and anabolics). So, the result can be less if you take it alone without additional hormones (thyroid hormone, insulin, steroids etc.).
3. Since HGH is available only on doctors’s prescription most bodybuilders take it on the black market. Thus, fake HGH may be the reason of their disappointment.
4. In rare cases your body may develop immune response to exogenous HGH. So, antibodies can neutralize its effect.

Thus, to get the optimal anabolic results you need to take insulin and LT-3 thyroid hormone (e.g. Cytomel) along with HGH. In this case the liver produces maximum amount of somatomedin and IGF. You can also increase anabolic effect by taking anti-catabolic substances – anabolic/androgenic steroids or Clenbuterol, which leads to synergy.

But one should also remember that Clenbuterol (as well as Ephedrine) reduces the natural production of insulin and L-T3. To get the massive and ripped look many professional bodybuilders take Kigtropin before the contest and reduce intake of calories at the same time.

Dosage and usage

As there are no scientific studies about Kigtropin application for performance improvement, the question of proper dosage and duration becomes difficult to answer. Thus, we have only empirical data. The manufacturer’s instruction says that in case of hypophysial stunting your weekly dose is 0.3 I.U/ week per pound of body weight. So, if your weight is 200 pounds, your weekly dosage will be 60 I.U. Divide the weekly dosage into three 20 I.U. intramuscular injections.

You can also make injections under the skin at the dose 8 I.U. every day. Professional athletes usually inject 4-16 I.U./day. As the half-life of HGH is less than 1 hour, some users divide their daily dosage into 3-4 subcutaneous injections of 2-4 I.U. each. Such division seems to be more effective and it makes sense.

We know that Kigtropin forces liver to produce IGF and somatomedins which provide the necessary result. As liver can produce only limited amount of above mentioned substances there is no need to stimulate it with larger dosages of HGH. So, smaller regular dosages are favorable.

One should also remember that if you don’t change the place of subcutaneous injections, it can lead to loss of fat tissue in this area (lipoathrophy). Thus, you have to always change the spot of injection.

Since the results of Kigtropin are dosage-dependent, do not begin using it if you don’t have enough money. Half measures will lead to failure. Don’t forget that minimal dose is 4 I.U. a day, meanwhile hypophysis of a healthy adult produces 0.5-1.5 I.U. of growth hormones a day.

Duration of Kigtropin course

The duration of the course also depends on your financial resources. Usually the cycle of Kigtropin lasts from six weeks to several months. The regular dosages make continuous improvement, but if you stop usage the effect may last for several weeks. Besides, many bodybuilders report that there is no loss of gained muscles after discontinuation.

Kigtropin and Insulin

If you take Kigtropin during build-up phase it’s not necessary to take exogenous insulin, but you need to eat sufficient meal every 3 hours (6-7 meals a day). This makes your body to continuously produce insulin, so that your blood sugar doesn’t fall to critical level. Usually during this phase athletes rarely take LT-3 thyroid hormones, but anyway you must consult a doctor and check the level of thyroid hormone if you take Kigtropin.

When you take insulin together with HGH, steroids and Clenbuterol, you have to remember that incorrect use of exogenous insulin can lead to obesity. The excess of insulin stimulates enzymes converting glucose into glycerol and eventually into triglycerides. Meanwhile shortage of insulin decreases the anabolic properties of HGH.

The solution in this case is to visit qualified doctor who will check your blood sugar and urine regularly and will give you advice as to insulin usage. Some bodybuilders inject moderately active insulin (generally Depot-H-Insulin Hoechst) which has 24 hour duration. There are also types of insulin with shorter duration, for example H-Insulin Hoechst has 8 hour duration, but bodybuilders rarely use it.

Side-effects

We have to underline that HGH has none of side-effects peculiar to steroids (low level of testosterone, acne, hair loss, aggression, gynecomastia, water retention, virilization in women). The only side-effects with HGH are abnormally low level of blood glucose (hypoglycemia) and disfunction of thyroid gland. Sometimes immune system develops antibodies against HGH , but it has no clinical aftermath.

As to the bone deformation, heart enlargement, gigantism and other horror stories we need to make difference between pre- and postpuberty humans. The thing is that the grow plates continue to elongate up to the puberty.

After that neither hypersecretion, nor the excess of exogenous growth hormone can cause the elongation of bones. Gigantism in humans is possible only in prepuberty period. Initially it goes along with outstanding strength and muscular hardness, but later, if untreated, leads to weakness and death.

Those who have hypersecretion of growth hormone after puberty, but stopped growing, can also suffer from acromegaly. In this case their bones become wider, but not longer. They have continuous growth of hands, feet, lower jaw and nose. Usually authorities take pictures of extreme cases to scare athletes, warning that if you take HGH you’ll have Neanderthal’s look. Nevertheless it is unlikely.

Though we don’t deny possible risks of exogenous HGH, but one should be realistic. Acromegaly, diabetes, dysfunction of thyroid gland, hypertrophy of heart, high blood pressure is possible only in case of excessive and prolonged usage. But in reality these cases are rare.

There are also reports about headaches, nausea, vomiting, and visual disturbances in the beginning of HGH usage. In most cases the symptoms vanish even if you continue usage. Usually problems begin when athletes inject improper dosages of insulin along with HGH.

Storage

Since HGH is a dried powder, you have to mix it with enclosed solution. Inject it immediately or store in a fridge for 24 hours maximum. As a rule dry growth hormone doesn’t lose its biological activity at the temperature 15-25 C (Saizen is exception). However the temperature of fridge (2-8° C) is better for its storage.

Availability

The HGH prices (Genotropin, Humatrope, Norditropin, and Saizen) on European black market may vary from $80 to $120 for a 4 I.U. vial including solution ampule. Beware of fakes. In USA growth hormone goes in mg (milligrams ) instead of I.U.(International Units). As 1mg is equal to 2.7 I.U., the 5mg solution of Humatrope contains 13.5 I.U. of HGH, correspondingly 10 mg solution of Protropin is equal to 27 I.U.

Usually bodybuilders prefer to take Humatrope than Protropin. This is due to additional amino acid in the sequence of Protropin (192 amino acids), meanwhile Humatrope is completely identical to natural hormone (191 amino acids). Probably this is the main reason why immune system produces antibodies mostly against Protropin than against Humatrope. Though growth hormone is considered as doping, it is not detectable in tests.