Liothyronine Sodium (Tiromel, Cytomel, T3)

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Description Liothyronine Sodium

There are three thyroid hormones: triiodide-thyronine (T3), L-thyroxine (L-T4) and thyrotrophic hormone which stimulates the release of T4. The major amount of T3 hormone in our body comes out of T4 conversion. Nowadays we have synthetic analogue of T3 hormone available on the market, which is called Cytomel.

Liothyronine Sodium (Cytomel / Tiromel, L-T3) is 4-5 times more active and has much quicker onset of the effect than L-T4. T3 has shorter half-life, possibly due to less plasma protein binding to thyroxine-binding globulin and transthyretin.

In medical practice Liothyronine Sodium (Tiromel) is widely used for treatment of thyroid insufficiency (hypothyroidism). Among the symptoms of hypothyroidism are metabolic disorders, obesity, and fatigue.

There is nothing hazardous in T3. It provisionally stops your thyroid function which can make a lag after supplementation unless you taper correctly. T3 may reduce your muscle mass, but you can avoid it by taking Anavar , Winstrol or Primobolan along with it. It also makes a good stack with clenbuterol.

Liothyronine Sodium in bodybuilding and fitness

T3 is a hormone that regulates oxidative metabolism in mitochondria. So, the higher the level of T3, the higher your metabolic activity is, thus you spend more energy and burn more fat. If you take low dosages of T3 along with steroids it may cause muscle growth due to the heightened metabolism. But high dosages of T3 start to burn both fat and muscles.

Bodybuilders usually take Liothyronine Sodium to induce metabolism which leads to quicker transformation of carbohydrates, proteins and fats. The increased fat burning represents special interest. Those who take part in competitions use Liothyronine Sodium (Tiromel) one week before the contest. It decreases the fat content without the need for hunger diet.

Simultaneous use of steroids along with Liothyronine Sodium improves the results of steroids, probably due to quicker conversion of proteins. All in all, Liothyronine Sodium is a good substitution for proviron in pre-contest cycles, especially for women.

If you combine T3 and Clenbuterol you can get synergetic effect. This happens due to proper regulation of beta 2 receptors in fat tissue, which Clenbuterol is inclined to deregulate. This combination results in enormous fat burning.

During T3 cycle it’s important to follow high-protein diet, non-bulking steroids (e.g. winstrol or primobolan) are also preferable. Otherwise you may greatly decrease muscle mass, especially during dieting. A combination of T3, Insulin, AAS, Winstrol/Primobolan and HGH can provide maximum results during short period of time.

Female usage

Liothyronine Sodium is very popular among women. Generally their metabolism is slower than in men, thus it’s more difficult for them to get the right form for the contest. Therefore they can avoid exhausting diet by taking Liothyronine Sodium. The ususal dosage for women is 50 mcg a day. A short-term course of Cytomel in proper doses is much healthier than exhausting hunger diet.

Cytomel Side Effects

T3 also causes the release of growth hormone (HGH). Since HGH is also a potent lipolytic substance it can lead to bigger decrease of muscle mass along with fat. You can avoid this side-effect by taking anabolic steroids along with T3+HGH combination.

The other possible side effects are: trembling hands, nausea, headaches, high perspiration, and increased heartbeat. Usually they disappear when you reduce the daily dosage.

Dosage and Usage of Cytomel T3

You should be very careful with Cytomel, as it is extremely powerful thyroid hormone. It is important that you begin with a low dose, raising it slowly and smoothly during several days. Most bodybuilders begin with one tablet a day (25 mcg), raising the dosage every 3-4 days by additional tablet. Do not exceed the dosage of 100 mcg a day. The daily dosage should be divided into three portions, thus it becomes more effective.

Do not take Cytomel for more than 6-8 weeks. You should abstain from the drug for at least 2 months after the end of the cycle. If you take Cytomel at high dosages and for a long time you may develop a chronic thyroid insufficiency.

In this case you will have to take thyroid hormones for the rest of your life. Do not stop the cycle abruptly, reduce the dosage gradually and smoothly. This method will let you safely recover thyroid function.

Before taking Liothyronine Sodium (Tiromel) you should consult your doctor to make sure that you don’t have hyperfunction of thyroid gland. If you take T3 for the first time it’s necessary to prolong the dosage increase period in order to see your reaction to T3 before taking high dosages.

If you use Liothyronine Sodium in mass gaining cycle (for better absorption of proteins) your dosage shouldn’t exceed 50 mcg a day. 25 mcg a day is even better in this case. During cutting cycles the dosage of Liothyronine Sodium must be higher.

T4 may also provide good results but the dosages differ. The ratio of T4 to T3 should be 4:1 or 4.5:1, so 100 mcg of T3 is equal to 400-450mcg of T4.

Example of Liothyronine Sodium cycle

The common tactics is to gradually increase T3 during 4-7 days till full dosage and then decrease it in the same way at the end of a cycle. However, thyroid is fast to shut down and hard to restart. Therefore you need to prolong the lowering period. For example you spend 5% of time on raising the dosage, then 40-50% of time on maximum dosage, so the rest of time goes on decreasing dosage. Thus you smoothly end the cycle and let your thyroid to recover.

Here is an example of a cycle for 3 weeks (25 tablets):

  • 4 days= 1, 1.5, 2, 3 tabs
  • 7 days= 4 tabs
  • 10 days = 3, 3, 2, 2, 2, 1, 1, 1, .5, .5 tabs

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