Anapolon [Anadrol 50] (Oxymetholone)

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Company: CS Balkan Pharmaceuticals Ltd. (Moldova)

Usage: oral

Description Anapolon (Oxymetholone)

Water retention is important in bodybuilding as it quickly increases diameter of muscles providing massive shape in a short time. As muscle cells consume a lot of water, most bodybuilders look smooth and sometimes puffy.

Anapolon is one of the substances that cause quantitative muscle gains greatly increasing strength. Since joints absorb water as well, it lubricates them, thus solving the joint problems in bodybuilders. Probably this is the main reason why most powerlifters take it.

How it works

By increasing the number of erythrocytes Anapolon provides muscle cells with more oxygen. It makes their endurance and performance level higher. Therefore bodybuilders taking Anapolon feel themselves full of strength even after several sets. Besides Anapolon is highly androgenic, which regenerates the body, thus making overtraining unlikely. It makes fantastic sensation when within hours after exhausting workout you feel fresh and ready for more.

Though Anapolon is not a pre-competition steroid, it can be more helpful than any steroid during dieting and intensive training. Most bodybuilders take it up to one week before contest, solving the water retention problem with anti estrogens and diuretics. These substances make them look bulky and hard.


The manufacturer of former Oxitosona 50 recommended a daily dosage of 0,5 – 2,5 mg per pound of body weight. Thus a 200 pound bodybuilder could take up to 500 mg a day, i.e. 10 tablets. We think that these doses are too high and can cause severe effects. A dosage of 0,5 – 0,8 mg per pound of body weight/day is enough for any bodybuilder.

This is about 1-4 tablets or 50-200mg daily. Do not exceed 4 tablets a day under any circumstances. But our opinion is that even 3 tab a day should not be exceeded. Those bodybuilders who just started with Anapolon should begin with no more than one 50 mg tab a day. And only after several days or a week you can increase the daily dose up to two tablets. Take them with meal, one in the morning and the other in the evening.

If you take a Nolvadex and Proviron along with a strict diet it can reduce water retention and even produce a noticeable increase in solid muscles. Bodybuilders taking Anapolon can feel a “pump effect” in the exercised muscles.Due to increased blood volume the muscles have higher blood supply during workout.

For advanced users

More advanced athletes or those weighing more than 220 pounds can increase the dosage up to 150 mg/day in the third week. We do not recommend taking Anapolon in this dosage for more than 2-3 weeks. After that, reduce the dose by one tablet every week. The usage of Anadrol 50 should not exceed 6 weeks, as it rapidly saturates receptors.

Dramatic mass gain which is observed shortly after beginning of Anapolon administration quickly decreases. So, either you have to increase the dose, which can lead to considerable side effects, or another substance should be taken. Those athletes who use Anadrol 50 for more than 5-6 weeks can gain up to 20 – 25 pounds.

Some consider these results satisfying and stop using the substance. It is important to shift to another steroid after discontinuation of Anapolon. Otherwise you may quickly lose all results, because there is no other AAS to cause so dramatic reduction in mass as does Anapolon. Injectable testosterones (Sustanon 250 or testosterone enanthate) for several weeks would be a good choice in this case.


Some athletes often stack Anapolon with Deca or Testosterone to gain mass and strength. The most popular combination among professional bodybuilders is Anapolon 100 mg+/day, Parabolon 228 mg+/week, and Sustanon 500 mg+/week. This combination is good for strength and mass build up but not suitable for steroid beginners.

Novices should experience “weaker” substances before using Anapolon. On the other hand there are fairy tales that professional bodybuilders take 10 -12 tabs of Anapolon a day. This is pure nonsense as it is much more than human body can handle, and “the more the better” is not correct in this case.

Side effects

Unfortunately Anapolon belongs to the most harmful steroids with considerable side effects. As it is 17-alpha alkylated it has liver toxicity. Thus most users experience certain changes in their liver values after several weeks. Oxymetholone easily transforms into estrogen thus causing feminization (gynecomastia etc.) and water retention.

Therefore it requires anti estrogens (Nolvadex, Proviron) and diuretics (Lasix) before a contest. If you got steroid acne after usage of Anapolon, than you can get rid of it by taking Accutane. Among other side-effects there are headaches, nausea, vomiting, stomach aches, lack of appetite, insomnia, and diarrhea.

There is also a feeling of general indisposition from administration of Anapolon. This is quite opposite to such substances as Dianabol, known for general well-being. Thus it makes quite strange situation when bodybuilder becomes stronger and bulkier, meanwhile he doesn’t feel well.

One should also mention that high level of androgen causes increased aggressiveness. This condition often occurs when you take high doses of testosterone along with Anapolon. It is not recommended for aged bodybuilders to take Anapolon as they are more sensitive to side effects. Therefore there is a high risk of prostate cancer and liver damage.

In order to build mass with this substance you need a calories-and-fat rich diet. Due to this fact the increase of LDL and decrease of HDL may occur. Besides, Anapolon reduces testosterone levels in the body. This happens due to inhibition of gonadotropin releasing hormone production (GnRH) in hypothalamus. For this reason you must take testosterone stimulating drugs such as HCG and Clomid to preserve testosterone production in testes.

Women and Anapolon

Anapolon is not suitable for women since it causes virilization and some of the symptoms are irreversible. They include increased hair growth (beard, legs etc.), hypertrophy of clitoris, increased libido, deep voice, hair loss, missed periods etc. Despite this fact some of female bodybuilders do take Anapolon during bulking phase. So, those women who want experience a bulking effect of Anapolon, but avoid androgenic side-effects, should take 25 mg (half a tablet) every two days.

This substance should be combined with such mild compounds as Primobolan Depot or Deca durabolin. Again we remind female bodybuilders that Anapolon is not for women and it’s up to you to take the risks. One should also mention that in medical practice Anadrol is used to treat bone marrow disorders and abnormalities of blood formation.

Reported Characteristics

  • Pharmaceutical Name: Oxymetholone
  • Chemical name: 17-beta-hydroxy-2-hydroxymethylene-17 alpha-methyl-5 alpha-androstan-3-one
  • Cutting/Bulking: Bulking
  • Anabolic Rating: 320
  • Active – Life: Less than 16 hours
  • Drug Class: Highly Androgenic / Anabolic Steroid (Oral)
  • Average Reported Dosage: Men 50-200 mg daily.
  • Acne: Yes
  • Water Retention: Extreme
  • High Blood Pressure: Yes
  • Liver Toxic: High
  • DHT Conversions: DHT-Derived
  • Decreases HPTA Function: Yes
  • Aromatization: No

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